Research Update: Exploring the Link Between Gut Microbiome, Nutrition, and Long-Term Health across Adulthood

We would like to share a brief update about an upcoming research study we are preparing on the gut microbiome—the trillions of microorganisms living in our digestive system—and its role in health and ageing.

Recent research highlights that the nutritional benefits of foods, and how our bodies respond to them, change as we age. These age-related changes are thought to be closely linked to shifts in the gut microbiome, which plays a central role in nutrient metabolism, inflammation, immune regulation, and communication with the brain (the gut–brain axis). As a result, the same diet may have very different effects on health in midlife compared to older age.

Age-related alterations in the gut microbiome have been associated with cardiometabolic conditions, cognitive decline, and frailty, while more diverse and resilient microbial profiles appear to support healthier ageing. Understanding these biological changes may help explain why personalized, age-specific nutritional and lifestyle strategies are increasingly important.

Our upcoming study in partnership with Dr. Jeremy Lim of AMILI aims to better understand how gut microbiome composition relates to nutrition and long-term health across adulthood, building on insights from our previous research on sleep, lifestyle, and ageing.

More information about the study and participation details will be shared in the near future, so please keep an eye out if this is of interest to you.